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EMCCDs Article Electron Multiplying Charge-Coupled Devices (EMCCDs)

By incorporating on-chip multiplication gain, the electron multiplying CCD achieves, in an all solid-state sensor, the single-photon detection sensitivity typical of intensified or electron-bombarded CCDs at much lower cost and without compromising the quantum efficiency and resolution characteristics of the conventional CCD structure.

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ORCA-R2 Digital Video Gallery

Fox Lung (FoLu) Cells with mEmerald-H2B and mCherry-Farnesyl

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The fluorescent protein Emerald and its monomeric form (mEmerald) were produced via the directed mutation of EGFP. Named for the gemstone with similar coloring, the green fluorescent proteins exhibit more brightness and photostability than their predecessor. The fox lung cells appearing in the digital video sequences presented in this section are shown expressing a mEmerald fusion tag with H2B, highlighting cell nuclei. The cells were additionally labeled with mCherry fused to farnesyl.