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EMCCDs Article Electron Multiplying Charge-Coupled Devices (EMCCDs)

By incorporating on-chip multiplication gain, the electron multiplying CCD achieves, in an all solid-state sensor, the single-photon detection sensitivity typical of intensified or electron-bombarded CCDs at much lower cost and without compromising the quantum efficiency and resolution characteristics of the conventional CCD structure.

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Pig Kidney (LLC-PK1) Cells with mEGFP Cx43

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Connexins are a family of proteins present in vertebrates that form intercellular channels in the plasma membranes of adjacent cells. These gap junctions facilitate free passage of ions and various small molecules between the cytoplasm of the cells. Connexins are most commonly named according to their molecular weights, though there are competing nomenclatures. mEGFP fused to connexin Cx43 was employed to visualize gap junctions in the pig kidney cell culture shown in the digital video sequence presented in this section.