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EMCCDs Article Electron Multiplying Charge-Coupled Devices (EMCCDs)

By incorporating on-chip multiplication gain, the electron multiplying CCD achieves, in an all solid-state sensor, the single-photon detection sensitivity typical of intensified or electron-bombarded CCDs at much lower cost and without compromising the quantum efficiency and resolution characteristics of the conventional CCD structure.

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Visualizing Endoplasmic Reticulum Dynamics

The endoplasmic reticulum (ER) is a vast network of flattened sacs and branching tubules that extends throughout the cytoplasm in plant and animal cells. These sacs and tubules are all interconnected by a single continuous membrane so that the organelle has only one large, highly convoluted and complexly arranged lumen (internal space). The digital videos in this section examine the dynamic action of endoplasmic reticulum membranes in cultured pig kidney cells.

Video 1 - Run Time: 40 Seconds - Dynamic endoplasmic reticulum activity is easily visualized in a single pig kidney epithelial cell. Choose a playback version: Streaming Video (7.5 MB), Progressive Download (7.5 MB), and MPEG Download (71 MB)

Video 2 - Run Time: 40 Seconds - A vast network of endoplasmic reticulum fills the cytoplasm and viewfield in this time-lapse video sequence. Choose a playback version: Streaming Video (7.5 MB), Progressive Download (7.5 MB), and MPEG Download (71 MB)

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